FUTURE OF TRAVEL President Donald Trump has wasted no time in upending his predecessor’s policies––from rescinding funding for EV charging infrastructure and proposing a slew of tariffs to initiating steps to revoke what he falsely calls the previous administration’s “EV mandate.” The moves have brought uncertainty and disruption to the US automotive industry at a time when leaders are navigating the costly transition to electric vehicles. Amid the chaos, medium-duty EV manufacturer Harbinger Motors aims to offer its customers a bit of certainty. The startup recently unveiled what it’s calling the “IRA Risk-Free Guarantee,” a program that promises price stability to customers if the commercial clean vehicle tax credit in the Inflation Reduction Act is rescinded. The 45W credit enables businesses to claim a credit of up to $40,000 on qualifying commercial vehicles. Harbinger’s Class 5 stripped chassis model with a 140 kilowatt-hour battery capacity, for example, currently sells for $103,200. “Buyers of this model will receive an IRA Risk-Free Guarantee credit of $12,900 at the time of purchase, bringing initial cost down to $90,300,” per a news release. “This matches the typical selling price of the equivalent Freightliner MT-45 diesel medium-duty stripped chassis, in addition to the Harbinger electric chassis offering enormous fuel and maintenance cost savings.” If the tax credit remains in effect as of next January, the customer would owe a second payment to Harbinger equal to the discount’s value. If the provision goes away, Harbinger would waive the second payment. Tech Brew recently spoke with John Harris, Harbinger’s CEO and co-founder, about the company’s decision to offer this guarantee and the ongoing federal policy changes. Keep reading here.—JG | |
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presented by Cytonics Osteoarthritis affects 365m+ people worldwide, and yet, there still isn’t an effective therapy that actually treats the root cause of the disease instead of merely masking symptoms. That may change, though. Cytonics entered the scene in 2019 with CYT-108, their experimental new therapy for osteoarthritis that has the potential to finally treat this debilitating disease. They’re now inviting investors to join their mission to eradicate osteoarthritis, once and for all. Here’s a quick breakdown of how their therapies work: - Cytonics’ tech centers on Alpha-2-Macroglobulin (A2M), a naturally occurring protein that can inhibit the enzymes that break down cartilage.
- Their lead drug candidate is a genetically engineered variant of A2M called CYT-108.
- CYT-108 doesn’t *just* alleviate symptoms—it addresses osteoarthritis at its root molecular source by blocking the enzymes that chew up cartilage.
Join Cytonics’ grassroots effort to fund drug development. |
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AI For all generative AI’s advances in language and reasoning, it’s still confined to our screens for now. That could eventually change as the tech industry steps up sci-fi-esque efforts to give this new intelligence a human-shaped shell. On that front, Nvidia last week rolled out a set of new tools for developers building humanoid robots, including what it says is the first open foundation model for leveling up their generalist capabilities, Isaac GR00T N1. The release comes as some high-profile startups and big AI companies are starting to explore ways to build AI advances into robotics. “The age of generalist robotics is here,” Nvidia CEO Jensen Huang said in the announcement. “With NVIDIA Isaac GR00T N1 and new data-generation and robot-learning frameworks, robotics developers everywhere will open the next frontier in the age of AI.” The model is pretrained with the ability to perform basic functions, like “grasping, moving objects with one or both arms, and transferring items from one arm to another,” as well as multistep tasks. Nvidia suggests these motor skills might be of use for functions like “material handling, packaging, and inspection.” Keep reading here.—PK | |
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Together With Chase for Business Grow with intelligence. Support the growth of your small business with Chase’s Customer Insights business intelligence platform.* It provides simple, actionable analytics to help business owners connect with customers, streamline operations, and make more informed decisions. It’s available at no extra cost when you accept credit card payments with Chase. Try it yourself.** |
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FUTURE OF TRAVEL “Disruption” is the word of the moment in the auto industry after President Donald Trump announced Wednesday that, starting next week, the US will impose a 25% tariff on all vehicles imported into the US. “While we’re still uncertain about exact policy outcomes, it looks like we are headed for the highest effective tariff rate since World War II,” Jonathan Smoke, Cox Automotive’s chief economist, said during a presentation Wednesday ahead of the announcement. “For the auto market, that is especially problematic, as such tariffs would be highly disruptive to North American vehicle production––resulting in tighter supply, higher prices, and lower production and sales.” What to know: The auto tariffs are slated to take effect at 12:01am ET on April 3, per Trump’s proclamation, which also stated that new import tariffs on car parts will go into effect by May 3. Car parts from Canada and Mexico that meet the requirements of the United States-Mexico-Canada Agreement will be exempt “until US Customs and Border Protections has a system in place to apply tariffs to non-US parts,” CNN reported. Underscoring the significance of the policy: About half the vehicles sold in the US are imports. Keep reading here.—JG | |
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Together With LaunchDarkly On guard. Protect new releases by mitigating risk right from launch day. LaunchDarkly Guarded Releases helps users detect app errors + performance problems ASAP. Teams can set and monitor performance thresholds and track performance metrics during the critical initial release window. The result? Delivering software safely without slowing progress. Check it out. |
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BITS AND BYTES Stat: 49%. That’s how much Tesla EV sales fell YoY in Europe in the first two months of 2025, the Associated Press reported, “even as overall sales of EVs grew.” Quote: “While I’m optimistic about the future of AI and technology in hearing aids, each new release from manufacturers seems to offer only incremental improvements compared to previous devices. I’m still waiting for that big breakthrough.”—Caroline Dadowski, a professor of audiology at Nova Southeastern University, to Healthcare Brew for a story about how AI is being used in hearing aids Read: How well do you know your own group chats? (The New York Times) Ache, ache, go away: Cytonics is creating therapies to potentially address osteoarthritis at its root molecular source—and they’re giving you a chance to invest in this possibly breakthrough tech. Get your investment in.* *A message from our sponsor. |
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THE FUTURE IS FULLY CHARGED The future of transportation is electric, autonomous, and AI-driven—so what’s next? Join us in New York or via livestream on May 29 as experts from energy, mobility, and policy explore the latest in EV and battery innovation, AI’s role in autonomous vehicles and traffic management, smart grid advancements, and the cybersecurity challenges of a connected transportation system. Don’t miss this look at the tech and trends shaping how we move—register now! |
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COOL CONSUMER TECH Usually, we write about the business of tech. Here, we highlight the *tech* of tech. DNA for sale; get your DNA here! In case you missed it, genetic testing company 23andMe filed for bankruptcy earlier this week, Healthcare Brew reported, meaning users’ genetic data could soon be up for sale. Wired has notes on how to delete your info from 23andMe’s databases. Speaking of data privacy: If you use any of Amazon’s Alexa voice assistants, “it’s a good time to revisit the terms of your relationship,” Washington Post tech columnist Shira Ovide writes in a column about the company’s plans to eliminate an option that allowed users to opt out of sending Alexa voice recordings back to Amazon. |
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JOBS Elevate your job search beyond the traditional channels. CollabWORK is where employers seek qualified candidates through trusted, community-based referrals. Let the power of community work for you, and click here to browse jobs curated especially for Tech Brew readers. |
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